International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)

RecruitingObservational study

Outcomes of Intra-arterial and Endosaccular Flow Diverters for Treatment of Intracranial Aneurysms - International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)

Who can join

Ages 18 and older · All sexes

Full eligibility criteria

Inclusion Criteria:

* Consecutive adult patients (18 years of age or older)
* Underwent endovascular treatment with one of the following devices:

  a. Endoluminal Flow Diverter Stents: i. Pipeline Flex (Covidien, California, USA) ii. Pipeline Flex with Shield Technology (Covidien) iii. Surpass Streamline (Stryker Neurovascular, California, USA) iv. Surpass Evolve (Stryker) v. Silk flow diverter (Balt Extrusion, Montmorency, France) vi. Flow-Redirection Intraluminal Device (FRED; MicroVention) vii. Flow-Redirection Intraluminal Device X (FRED X; MicroVention) viii. p64 Flow Modulation Device (phenox GmbH) ix. Endovascular clip system (eCLIPs) (eCLIPsTM, eVasc Neurovascular, Vancouver, BC, Canada)

  b. Intrasaccular Flow Disruptors: i. Woven EndoBridge (WEB; MicroVention) ii. Luna/Artisse System (Medtronic) iii. Medina Embolic Device (Medtronic) iv. Contour Neurovascular System (Cerus Endovascular) v. Neqstent Coil Assisted Flow Diverter (Cerus Endovascular) vi. pCONus and pCANvas (phenox GmbH) vii. Nexus Aneurysm Embolization System (EndoStream Medical) viii. CITADEL™ Embolization Device (Balt, USA)
* Complete medical records and follow-up data available

Exclusion Criteria:

* Incomplete procedural or follow-up records
* Non-flow-diverter or non-flow-disruptor treatments (e.g., coiling-only cases)
* Aneurysms treated with investigational devices not listed within Inclusion Criteria

About the study

This multicenter retrospective cohort study aims to evaluate and compare the technical performance, safety, and clinical outcomes of intracranial aneurysms treated with flow diverter stents and endosaccular flow disruptors.

Sponsor: Montefiore Medical Center · Participants: 5,000 · Started: Oct 1, 2023

Contact the study team

Muhammed Amir Essibayi, MD · Phone: 347-908-1889

Official record on ClinicalTrials.gov — NCT06174727

Locations in the U.S.

Florida	University of Miami, Coral Gables
Massachusetts	Lahey Hospital and Medical Center, Burlington
Michigan	Munson Medical Center, Traverse City
Minnesota	Allina Health, Minneapolis
New Jersey	Robert Wood Johnson University, New Brunswick
New York	Montefiore Medical Center Department of Neurosurgery, The Bronx

Conditions

Brain Aneurysm

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.