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Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

RecruitingHealthy volunteers welcome

SR2204: A Randomized Phase III Trial of a Perioperative Physical Activity Intervention in Older Adults With Lung Cancer and Their Family Caregivers

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* PATIENT: Documented informed consent of the participant and/or legally authorized representative
* PATIENT: Agreement to allow the use of preoperative chest CT scan for exploratory analysis, if available
* PATIENT: Agreement to wear pedometer during study duration

  * If unwilling, exceptions may be granted with study primary investigator (PI) approval
* PATIENT: Age \>= 65 years
* PATIENT: Ability to read and understand English or Spanish and willingness to complete participant-reported outcomes and assessments
* PATIENT: Diagnosis of lung cancer or presumed lung cancer (as determined by surgeons) in patient
* PATIENT: Scheduled to undergo lung surgery for lung cancer or suspected lung cancer with curative intent (neoadjuvant therapy allowed)
* PATIENT: Adults lacking capacity to consent in the opinion of the attending surgeon will not be enrolled
* FCG: Documented informed consent of the participant and/or legally authorized representative
* FCG: Age \>= 18
* FCG: Ability to read and understand English or Spanish and willingness to complete participant-reported outcomes and assessments
* FCG: Adults lacking capacity to consent in the opinion of the attending surgeon will not be enrolled

Exclusion Criteria:

* PATIENT: Lung surgery is scheduled in less than 14 calendar days from the time of registration
* PATIENT: Prospective participants who, in the opinion of the investigator, may not be able to comply with all study procedures (including exercise program and compliance issues related to feasibility/logistics)
* FCG: Prospective participants who, in the opinion of the investigator, may not be able to comply with all study procedures (including exercise program and compliance issues related to feasibility/logistics)

About the study

This clinical trial compares telephone-based physical activity coaching to self monitored physical activity for improving physical function in older adults who are undergoing surgery for lung cancer and their caregivers. Lung cancer surgery in older adults is associated with functional declines and unique challenges. Performing physical activity around the time of surgery has been shown to improve functional outcomes in patients and exercise programs delivered via telehealth may improve access and convenience for patients and minimize participant burden. Telephone-based physical activity coaching may improve physical functioning for older adults with lung cancer who are undergoing surgery.

What is being tested

Sponsor: City of Hope Medical Center · Participants: 382 · Started: Dec 5, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT06196008

Locations in the U.S.

CaliforniaUniversity of California, Davis
City of Hope Medical Center, Duarte
City of Hope at Irvine Lennar, Irvine
Standard University, Stanford
City of Hope at Upland, Upland
ConnecticutYale New Haven Medical Center, New Haven
FloridaMoffitt Cancer Center, Tampa
GeorgiaCity of Hope at Georgia - Atlanta, Newnan
IllinoisNorthwestern University, Evanston
MassachusettsMassachusetts General Hospital (MGH) / Harvard, Boston
Lahey Hospital & Medical Center, Burlington
MississippiUniversity of Mississippi Medical Center, Jackson
North CarolinaDuke University, Durham
OhioOhio State University, Columbus
TennesseeBaptist Clinical Research Institute, Memphis
TexasMD Anderson Cancer Center, Houston

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.