Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits
Improving Reading Competence in Aphasia With Combined Aerobic Exercise and Phono-Motor Treatment
Who can join
Ages 18 to 85 · All sexes
Full eligibility criteria
Inclusion Criteria: * fluent and literate in English prior to stroke * 1st ever stroke * more than 3 months post-stroke * post-stroke reading deficits, defined as reading aloud accuracy \<83% for single words or \<65% for readable nonwords * living within a 50-mile radius from Kessler Foundation. Exclusion Criteria: * contraindication to MRI * prior neurological disease * developmental learning or reading disability (i.e., developmental dyslexia) * contraindication to exercise * concurrent speech and language therapy
About the study
The goal of the proposed project is to test the effectiveness of a novel hybrid approach to treatment of reading disorders after stroke, in which exercise training will be used in combination with a targeted reading treatment. This approach is expected to increase cerebral circulation and help to rebuild and strengthen the damaged phonological neural networks. Through this combinatory approach, the study aims to enhance the reading and language improvements seen with existing treatments.
What is being tested
- Phono-Motor Therapy (behavioral)
- Aerobic Exercise Training (AET) (behavioral)
- Stretching (behavioral)
Sponsor: Kessler Foundation · Participants: 70 · Started: Apr 18, 2024
Contact the study team
- Olga Boukrina, PhD · Phone: 19733243587
- Matthew R Weiner · Phone: 973-323-3745
Official record on ClinicalTrials.gov — NCT06213272
Locations in the U.S.
| New Jersey | Kessler Foundation, West Orange |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.