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A Biomechanical Evaluation of the Ossur Power Knee in Persons With Transfemoral Amputation

Do Transfemoral Prostheses With Powered Prosthetic Knee Flexion and Extension Improve Mobility? A Biomechanical Evaluation of the Ossur Power Knee

Who can join

Ages 45 to 75 · All sexes

Inclusion Criteria:

* Unilateral, transfemoral amputation (any etiology)
* Residual limb length classified as standard (i.e., medium) to long
* Prosthesis user for at least 1 year prior to enrolling in the study
* K3 or K4 level ambulator
* Good sensation on their residual limb(s) (upon routine clinical examination)
* Good skin integrity upon visual inspection
* Does not require the use of assistive devices to walk for short distances
* Not currently taking medications that are known to affect balance or gait
* Presents with good socket fit based upon a standard assessment by the study prosthetist

Exclusion Criteria:

* Bilateral amputations
* Individuals with a knee disarticulation

About the study

Microprocessor-controlled knees (MPKs) do not typically utilize motors to power joint rotation, but they automatically adjust resistance or damping in the joint to improve swing- and/or stance-phase control as appropriate for the prosthesis user during gait. The Ossur Power Knee is the only commercially-available MPK that uses a motor to provide active power generation during walking and other activities. The purpose of this proposed investigation is to perform and compare biomechanical evaluations of the Power Knee and Ossur Rheo XC, a passive MPK, during walking and other activities by prosthesis users. Furthermore, mobility between male and female subjects will be compared to determine if there are differences in prosthetic knee usage on the basis of sex.

What is being tested

• Powered prosthetic knee joint (other)
• Conventional microprocessor-controlled prosthetic knee joint (other)

Sponsor: VA Office of Research and Development · Participants: 20 · Started: Apr 1, 2024

Contact the study team

• Rebecca Stine, MS · Phone: (312) 503-5726
• Steven A Gard, PhD · Phone: (312) 503-5718

Official record on ClinicalTrials.gov — NCT06218238

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.