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Prostate Single Port & Laser Enucleation Comparison Trial

Recruiting

Randomized Controlled Trial Comparing Single Port Simple Prostatectomy and Laser Enucleation of the Prostate for Benign Prostatic Hyperplasia

Who can join

Ages 18 to 88 · Men

Full eligibility criteria
Inclusion Criteria:

* Patients diagnosed with symptomatic Benign Prostatic Hyperplasia (BPH) who fail conservative treatment with drug therapy are eligible for surgical intervention.

Exclusion Criteria:

* Adults unable to consent Prisoners Cognitive impaired adults Coagulopathy

About the study

Surgical treatments for benign prostatic hyperplasia (BPH) are necessary when non-procedural approaches fail to alleviate lower urinary tract symptoms (LUTS) or bladder outlet obstruction (BOO). Open simple prostatectomy and laser enucleation are recommended for prostatic adenoma size greater than 80 ml. Minimally invasive approaches, such as robotic-assisted simple prostatectomy, have gained popularity due to their comparable outcomes with lower morbidity. The introduction of the da Vinci single-port (SP) robotic platform offers potential advantages, but its outcomes have not been thoroughly investigated.

This randomized controlled trial aims to compare the outcomes of SP simple prostatectomy performed using the da Vinci robotic platform versus thulium laser enucleation of the prostate for the treatment of BPH and BOO.

What is being tested

Sponsor: University of Illinois at Chicago · Participants: 116 · Started: Jan 15, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06224218

Locations in the U.S.

IllinoisUI Health SCB Clinic Department of Urology, Chicago

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.