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To Develop a Walking Exercise Program for Non-ambulatory Stroke Survivors

Recruiting

Who can join

Ages 18 to 80 · All sexes

Full eligibility criteria
Inclusion Criteria:

* must be 18 to 80 years old
* male or female
* independent ambulation before stroke
* able to understand and follow verbal commands in English
* have physicians' approval for exercise
* be in a stable medical condition
* must be after the first stroke
* unable to walk independently
* in the chronic stage (at least 6 months after stroke onset)

Exclusion Criteria:

* musculoskeletal or other disorders that prevent the participant from participating in the exercise
* blood pressure higher than 200/110 mm Hg
* diagnosis of severe depression
* functionally restricted passive movement in the major joints of lower limbs
* unable to speak or understand English
* unable to travel to the Research Laboratory
* currently participate in other walking training using treadmill with or without a body-weight support system
* body weight greater than 400 lbs

About the study

The goal of this clinical trial is to test a gait (walking) training program in non-ambulatory (unable to walk) chronic stroke survivors. The main question it aims to answer is:

• Will gait training improve the cardiovascular system in non-ambulatory chronic stroke survivors better than a sitting leg cycling exercise?

Participants will walk on a treadmill with a partial body-weight support system and the gait training device. Researchers will compare with a leg-cycling exercise to see if there are significant differences in resting heart rate, systolic blood pressure (SBP), and A1c levels in the blood.

What is being tested

Sponsor: University of Kansas Medical Center · Participants: 72 · Started: Feb 2, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06247553

Locations in the U.S.

KansasUniversity of Kansas Medical Center, Kansas City

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.