Home › Lung Cancer › NCT06252129

Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria:

1. Subjects with a lung nodule or mass who are eligible to undergo a lobectomy.
2. Subject without any metastasis present.
3. Subjects who have peripheral lung nodule location
4. Subjects must be 18 years of age or older.

Exclusion Criteria:

1. Subjects who received preoperative chemotherapy or radiotherapy.
2. Subjects who have a lung nodule located in a central location. Central tumors are defined by those infiltrating the lobar airway.

About the study

Lung cancer patients undergoing upfront surgery, highly benefit from a systematic lymph node dissection in the mediastinum and in the surgical specimens. The latter is performed by the pathologist. Developing a standardized technique to dissect the lobectomy specimen has the potential of maximizing the retrieval of all N1 stations lymph nodes. The investigators believe that the adoption of such technique will improve lung cancer staging and identify a higher number of patients that qualify for adjuvant therapies.

What is being tested

• Subjects undergoing a lung specimen lymph node dissection (other)
• Control group (other)

Sponsor: Brigham and Women's Hospital · Participants: 160 · Started: Jul 26, 2024

Contact the study team

• Paula Ugalde Figueroa, M.D. · Phone: (617) 732-7696

Official record on ClinicalTrials.gov — NCT06252129

Locations in the U.S.

Conditions

• Lung Cancer
• Lymphatic Metastasis

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.