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InformationSeekingMesolimbicEngagementStudy2

The Influence of Mesolimbic-hippocampal Interactions on Episodic Memory During Active Information Seeking

Who can join

Ages 18 to 45 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* 20/40 far acuity (either corrected or uncorrected)
* In good medical health

Exclusion Criteria:

* History of head injury
* History of illness with Central Nervous Systems implications
* On Medications that Affect blood flow response and alertness
* Consumption of smoking and/or coffee 30 minutes prior to laboratory testing
* Placement of a device contraindicated for magnetic resonance imaging including cardia pacemaker, aneurysm clip, cochlear implants, pregnancy, intra-uterine device, shrapnel, metal fragments in the eyes, neurostimulators
* Weight \> 250lbs
* Claustrophobia

About the study

Participants will complete a treasure task during neuroimaging where they have to learn which keys open a treasure chest, and then they are tested on the contents of the treasure chest.

What is being tested

• Task Instructions (behavioral)

Sponsor: Temple University · Participants: 80 · Started: Oct 24, 2023

Contact the study team

• Vishnu Murty, PhD · Phone: 7406328932

Official record on ClinicalTrials.gov — NCT06257433

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.