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Virtual Reality for Non-cardiac Chest Pain

A Feasibility Study of Virtual Reality for the Treatment of Non-cardiac Chest Pain

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Symptoms of non-cardiac chest pain (recurrent anginal-like or atypical chest pain)
* Negative prior cardiac evaluation (at a minimum, including electrocardiogram)
* Prior esophagogastroduodenoscopy and/or barium esophagram to rule out severe esophagitis, stricture, or motility abnormality

Exclusion Criteria:

* Initiation of a proton pump inhibitor (PPI) within 8 weeks
* Major concomitant illness
* Current drug or alcohol use that that would interfere with adherence to study requirements
* Symptoms of vertigo or dizziness that would limit tolerability of the VR headset

About the study

The purpose of this study is to determine if virtual reality (VR) will improve symptoms in non-cardiac chest pain (NCCP).

What is being tested

• Virtual Reality (other)

Sponsor: Mayo Clinic · Participants: 10 · Started: Feb 14, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06262126

Locations in the U.S.

Conditions

• Chest Pain

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.