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Effect of Raised End-Tidal pCo2 on Choroidal Volume

Who can join

Up to age 8 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* any child undergoing an eye exam under anesthesia for an ophthalmologic reason.
* children between the ages newborn to 8 years of age.

Exclusion Criteria:

* children who are not having an eye exam under anesthesia.
* children with a known medical diagnosis that affect the eye to be studied
* \* children over the age of 8 years of age.
* \* children with altered cerebral autoregulation, increased intracranial pressure, pulmonary hypertension, or any other condition deemed appropriate by the anesthesiologist.
* children in whom a laryngeal mask airway will not be used

About the study

This study is to investigate the relationship between arterial carbon dioxide (CO2) concentration and vitreous pressure on the choroidal volume by integrated intraoperative OCT imaging under eye exams under anesthesia.

What is being tested

• Ventilation manipulation (other)

Sponsor: University of Pittsburgh · Participants: 20 · Started: Feb 27, 2023

Contact the study team

• Amy Monroe, MPH, MBA · Phone: 412-623-6382
• Alisha Maslanka, BS, CCRC · Phone: 412-491-2748

Official record on ClinicalTrials.gov — NCT06275308

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.