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Mix of Demineralized Freeze-Dried Bone Allograft and Deproteinized Bovine Bone Mineral: a Possible Solution for Alveolar Ridge Preservation?

RecruitingHealthy volunteers welcome

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Patients in good health
* Require the extraction of at least one premolar or molar with future implant placement
* Sufficient keratinized gingiva (equal or more than 2mm prior to extraction),
* No more than 3mm of buccal bone loss
* Flapless extraction possible
* Full mouth plaque index of less than 25%

Exclusion Criteria:

* Nicotine consumption equivalent to or more than 10 cigarettes per day
* Electronic cigarette usage
* A history of irradiation of head and neck area
* Immunodeficiency disease
* Uncontrolled systemic health problems (hypertension crisis 180/120, hyperthyroidism, diabetes with HbA1c over 7, recent history of stroke, cancer) History of medications that affect bone remodeling process (bisphosphonates, RANK-L inhibitors)
* Previous adverse reaction to the biomaterials used
* Pregnancy/lactation, or those who are trying to become pregnant.
* Active uncontrolled or untreated periodontal disease
* Periapical lesions greater than 1 cm and soft tissue pathology

About the study

The purpose of the study is to compare a new grafting material for alveolar ridge preservation to a commonly used and well studied material. Alveolar ridge dimensions as well as histology will be compared.

What is being tested

Sponsor: Nova Southeastern University · Participants: 30 · Started: Jan 26, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06275789

Locations in the U.S.

FloridaNova Southeastern University, Fort Lauderdale

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.