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Behavioral and Cognitive Predictors of Persistent Pain and Opioid Misuse in Chronic Pain

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* With diagnoses related to chronic lower back pain
* Age above 18yrs
* Non pregnant

Exclusion Criteria:

* Cancer pain

About the study

Chronic lower back pain (CLBP) affects approximately 20% of the global population. The study objective is to determine if impulsivity, inhibitory control, drug choice, and/or cognitive distortions predict opioid misuse and disability in patients with chronic pain. This is a prospective consented cross-sectional study characterizing behavioral and cognitive phenotypes using both patient-reported survey measures and cognitive testing. Outcome measures include correlations between impulsivity measures, opioid drug choice responses and cognitive distortion scores, and risk for opioid misuse (Primary outcomes: COMM scores, SOAPPR scores). Secondary outcomes is BPI measurement. A Certificate of Confidentiality will provide additional protections for participants.

What is being tested

• No Intervention (other)

Sponsor: Icahn School of Medicine at Mount Sinai · Participants: 130 · Started: Dec 20, 2023

Contact the study team

• Chinwe Nwaneshiudu, MD PhD · Phone: 212 241 4203

Official record on ClinicalTrials.gov — NCT06288282

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.