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Ostomy Primary Closure With 0.1% Betaine/Polyhexanide Wound Irrigation Compared to Pursestring Closure
To Close or Not to Close: Surgical Site Infection Rates in Ostomy Primary Closure With 0.1% Betaine/Polyhexanide Wound Irrigation Compared to Conventional Ostomy Closure by Secondary Intention
Who can join
Ages 18 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * All patients 18 years or older with an diverting loop ileostomy reversal indication will be enrolled * Signed consent Exclusion Criteria: * Under 18 years old, unable to provide consent, has a parastomal hernia requiring mesh repair, or has an end ileostomy
About the study
The goal of this clinical trial is to compare two types of closure in patients with ostomies that are ready for closure. The main questions it aims to answer are:
1. Surgical site infection rates 2. Patient quality of life 3. Time to wound healing
Participants will undergo either complete ostomy wound closure after washing out the wound with Prontosan, or their ostomy wound will be closed using the Pursestring method, where the wound will be left partially open and allowed to heal from the inside out. Researchers will compare these two groups' outcomes (questions to be answered) as listed above.
What is being tested
- Primary Ostomy Closure with 0.1% Betaine/0.1% Polyhexanide Wound Irrigation (drug)
- Pursestring Closure (procedure)
Sponsor: University of Nevada, Las Vegas · Participants: 84 · Started: Mar 14, 2024
Contact the study team
- Abigail W Cheng, MD · Phone: 9166954159
- Lance Horner, MD · Phone: 7755445456
Official record on ClinicalTrials.gov — NCT06309368
Locations in the U.S.
| Nevada | University Medical Center, Las Vegas |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.