Home › NCT06311617

Retinal Vascular Changes During Pregnancy

Understanding Retinal Vascular Changes During Pregnancy and the Impact on Maternal and Fetal Health

Who can join

Ages 18 and older · Women

Inclusion Criteria:

1. Patient age 18 years and older
2. Patient able to provide informed consent
3. Pregnant at time of enrollment and in the 1st or 2nd trimester of pregnancy

Exclusion Criteria:

1. Other ocular disease that prevents imaging (significant cataract or other media opacity)
2. Unable to comply with imaging or follow-up through duration of study

About the study

The goal of this study is to better understand how the back part of the eye-called the retina and the choroid-changes during pregnancy. Specialized photos of the eye will be taken at three different timepoints: early in pregnancy (first or second trimester), late in pregnancy (third trimester), and after delivery. This imaging is non-invasive and does not require contact with the surface of the eye. The photos taken will allow assessment of specific parameters, like blood flow and the health of specialized cells that support vision. Understanding how the eyes change during pregnancy may help guide how retina specialists understanding of retinal disease during pregnancy and better inform pregnancy outcomes.

What is being tested

• Optical coherence tomography (diagnostic test)

Sponsor: Vanderbilt University Medical Center · Participants: 90 · Started: Feb 1, 2024

Contact the study team

• Saige Priddy · Phone: 615-936-2020
• Elise Timtim, MD · Phone: 615-936-2020

Official record on ClinicalTrials.gov — NCT06311617

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.