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Physical Activity to Mitigate PreEclampsia Risk

RecruitingHealthy volunteers welcome

Physical Activity to Mitigate PreEclampsia Risk (PAMPER)

Who can join

Ages 18 to 40 · Women · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* healthy women, age 18-40 years, \<16 weeks' gestation, with singleton pregnancy; women (BMI:18.5-45.0), sedentary, cleared by their obstetric provider.

Exclusion Criteria:

* pre-existing chronic conditions such as HIV, lupus, etc.; taking medicines that affect fetal development; and/or lack of telephone or email contact information).

About the study

The purpose of this study is to compare the effects of aerobic (AE), resistance (RE), and combination (AERE) exercise throughout pregnancy on selected maternal and fetal/neonatal physiological variables in women at-risk for preeclampsia. The central hypothesis of this project is that exercise will decrease severity and occurrence of preeclampsia symptoms, thus improving maternal, pregnancy, and birth outcomes.

Aim 1. Determine the influence of different exercise modes during pregnancy at risk of preeclampsia on maternal cardiometabolic health.

Aim 2. Determine the most effective exercise mode in pregnancy at risk of preeclampsia on improving birth and infant health outcomes.

What is being tested

Sponsor: East Carolina University · Participants: 224 · Started: Jun 24, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06319014

Locations in the U.S.

North CarolinaEast Carolina University, Greenville

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.