Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department
Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department Using Wrist Accelerometer Biosensors and Machine Learning
Who can join
Ages 65 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * adults patients 65+ years old with a known diagnosis of dementia or medical team highly suspects or confirms dementia this visit. * Emergency Department visit and/or hospitalization anticipated to last \>4 more hours from the time of enrollment. Exclusion Criteria: * Intubation/mechanical ventilation * Patients undergoing a procedure requiring sedation * Patients who cannot consent due to cognitive impairment and do not have a legally authorized representative or caregiver present.
About the study
Delirium is highly prevalent and very bad for patients with dementia. Delirium is a dangerous medical condition that occurs in 6-38% of older Emergency Department patients and 70% of ICU patients. A person who develops delirium in the ED or hospital has a 12 times higher odds of being newly diagnosed with dementia in the next year compared to a similar patient who does not become delirious. Delirium is especially dangerous for persons living with Alzheimer Disease and Related Dementias (AD/ADRD). Persons living with ADRD have an almost 50% chance of developing delirium in the hospital.
Clinicians are bad at recognizing delirium. A recent systematic review led by the Geriatric Emergency Care Applied Research network (NIH funded) found that current delirium screening tools are at most 64% sensitive, meaning that physicians can identify some phenotypes of delirium well, but cannot easily rule out delirium in acutely ill older patients.
The investigators propose integrating wrist biosensors into the emergency management of older adults with dementia. The investigators will monitor heart rate variability, movement, and electrodermal activity (electrical activity of at the level of the skin) to determine if an array of biosensors more sensitive to delirium than current verbal screening tools.
What is being tested
- Empatica EmbracePlus (device)
Sponsor: Ohio State University · Participants: 60 · Started: Apr 10, 2024
Contact the study team
- Lauren Southerland, MD MPH · Phone: 614-366-8375
Official record on ClinicalTrials.gov — NCT06326424
Locations in the U.S.
| Ohio | The Ohio State University Wexner Medical Center, Columbus |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.