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Gentamicin Bladder Instillation on CAUTI

A Randomized Controlled Trial to Evaluate the Effectiveness of Gentamicin Bladder Instillation on CAUTI

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

1. age greater than 18
2. admitted with a trauma, surgical, or neuro-critical care diagnosis
3. indwelling foley catheter in place

Exclusion Criteria:

1. Documented positive UA or Urine Culture within the past 7 days or upon admission
2. Traumatic bladder injury
3. Gross hematuria
4. Chronic indwelling urethral or chronic suprapubic foley catheter
5. allergy to gentamicin or similar aminoglycosides

About the study

Urinary tract infections in catheterized patients is an unacceptable complication and has been termed a 'never event' by the Center for Medicare \& Medicaid Services (CMS); however there is not consensus among clinicians on how to best prevent CAUTIs. We propose a prospective randomized controlled trial to test the efficacy of prophylactic gentamicin bladder irrigation in elimination of CAUTIs.

What is being tested

• Gentamicin (drug)

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix · Participants: 400 · Started: Oct 9, 2023

Contact the study team

• Kristina M Kupanoff, PhD · Phone: 602-406-5192
• Hahn Soe-Lin, MD · Phone: 602-406-3874

Official record on ClinicalTrials.gov — NCT06332040

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.