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Quantitative Assessment of Autologous Fat Transfer

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

Age of 18 years or older

* Planned autologous fat transfer or fat grafting reconstruction of the breast or chest wall.
* Able to provide written or electronic informed consent.
* Able to undergo MRI.

Exclusion Criteria:

* Vulnerable subjects (children, prisoners, pregnant women).
* Patients who have active cancer, metastatic disease, solid organ transplantation / immunosuppression, or autoimmune diseases.
* Unable to undergo MRI (history of metal contraindication, claustrophobia)

About the study

This is a single-arm, prospective pilot study that will objectively assess outcomes in patients electively undergoing Autologous Fat Transfer (AFT) for breast or chest wall reconstruction. Patients planning to undergo autologous fat transfer for breast or chest wall reconstruction will be enrolled prospectively. Participants will undergo standard photographs (2-D imaging) of their chest wall and torso, including the breasts, and complete a validated questionnaire (BREAST-QTM) to evaluate patient satisfaction, and quality of life, all standard of care. The 3D photographs, Magnetic resonance imaging (MRI), and Ultrasound (US) are routinely used in practice but will be performed for research purposes in this study. All imaging procedures and questionnaires will be obtained at baseline and follow-up visits 3-6.

What is being tested

• 2-Dimensional (2-D) Photographs (Visit 1/ Follow up Visit 3-6) (procedure)
• 3-Dimensional (3-D) Photographs (Visit 1- 6) (procedure)
• Ultrasound Soft Tissue Assessment (Visit 1/ Follow up Visit 4-6) (procedure)
• Magnetic Resonance Imaging Volume Assessment (Visit 1/ Follow up Visit 4-6) (procedure)
• BREAST-QTM questionnaire (Visit 1/ Follow up Visit 4-6) (procedure)

Sponsor: University of Chicago · Participants: 15 · Started: Jan 25, 2024

Contact the study team

• Summer Hanson, MD · Phone: 773-702-6302

Official record on ClinicalTrials.gov — NCT06343831

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.