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Biomarkers to Predict Cancer Therapy-related Cardiotoxicity
RecruitingObservational study
Biomarkers to Predict Cancer Therapy-Related Cardiotoxicity
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * 18 years of age or older * Treated for any malignancy with any type of chemotherapy including oral, parenteral therapy and immunotherapy * One of the following: * Diagnosed with cardiotoxicity defined as; cardiomyopathy, symptomatic heart failure, asymptomatic reduced systolic function, acute coronary syndrome, myocardial infarction, critical limb ischemia, cardiac arrhythmias or myocarditis possibly related to prior cancer treatment * Completed chemotherapy with no cardiotoxicity at least two years post treatment * Patients with cancer who will be initiating systemic therapy with potentially cardiotoxic medications. This will include chemotherapy, immunotherapy, targeted therapy that have been associated with cardiac toxicity * An understanding of the protocol and its requirements, risks, and discomforts * The ability and willingness to sign an informed consent Exclusion Criteria: \- Inability on the part of the patient to understand the informed consent or be compliant with the protocol
About the study
This study evaluates why some cancer patients but not others experience changes in heart function following treatment with chemotherapy.
What is being tested
- Non-Interventional Study (other)
Sponsor: Mayo Clinic · Participants: 693 · Started: May 3, 2019
Contact the study team
- Clinical Trials Referral Office · Phone: 855-776-0015
Official record on ClinicalTrials.gov — NCT06353191
Locations in the U.S.
| Arizona | Mayo Clinic in Arizona, Scottsdale |
| Florida | Mayo Clinic in Florida, Jacksonville Moffitt Cancer Center, Tampa |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.