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Linking Somatic Mutation Rate With Baseline Exposure in East Palestine
Healthy Futures Research Study: Linking Somatic Mutation Rate With Baseline Exposure in East Palestine
Who can join
Ages 18 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Residence on February 3rd, 2023 in Columbiana County, Ohio, Mahoning County, Ohio, Beaver County, PA, or Lawrence County, PA. * Current residence in the United States. Exclusion Criteria: * Address provided for February 3rd, 2023 not in Columbiana County, Ohio, Mahoning County, Ohio, Beaver County, PA, or Lawrence County, PA * Invalid address provided for February 3rd, 2023 residence.
About the study
The goal of this study is to This research team is conducting this study to develop methods to measure the biological impact of exposure to the chemicals released following the February 3, 2023 train derailment on residents of East Palestine, Ohio, and surrounding communities. The main question it aims to answer is:
* What biological impact will be measured based on DNA damage? * In participants who provide a biospecimen, how are biomarker changes related to proximity to the derailment and variations in residents' health histories and behaviors?
Participants will:
* Complete a brief survey asking about experiences related to the February 3, 2023 train derailment, health experiences, and concerns following the derailment, and background information regarding health history. * Possibly contribute biospecimens such as blood, spit, hair, and/or toenail clippings. * Receive communication about study updates and future research opportunities. * A total of 40 study participants will be recruited to participate in a 90-minute interview. The interviews will be video and audio recorded.
What is being tested
- Survey (other)
- Biological specimen collection (other)
- Communications about study updates and future research opportunities (other)
- Qualitative interview (other)
Sponsor: Case Comprehensive Cancer Center · Participants: 500 · Started: Aug 16, 2024
Contact the study team
- Fredrick R Schumacher, PhD · Phone: 216-368-0351
Official record on ClinicalTrials.gov — NCT06357845
Locations in the U.S.
| Ohio | Case Western Reserve University, Case Comprehensive Cancer Center, Cleveland |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.