Home › Autism Spectrum Disorder › NCT06362733

Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth

Who can join

Ages 4 to 17 · All sexes · Healthy volunteers welcome

Participants will include children with:

1. parent/guardian aged 18 years or older with a child aged between 4.0 to 17.11 years old at the time of parental consent;
2. diagnosed with ASD (based on history, review of available medical records including diagnostic testing, e.g., ADOS) or suspicion of ASD diagnosis and confirmed with Autism Diagnostic Interview-Revised (ADI-R);
3. parent-reported clinically significant concerns regarding insistence on sameness and behavioral inflexibility;
4. stable behavioral and pharmacological treatment for at least two weeks with no anticipated changes;
5. English-speaking parent and youth able to consistently participate in study procedures;
6. family resides in United States.

About the study

The purpose of this open label trial is to examine the preliminary feasibility, acceptability, and effectiveness of a 12-week behavioral intervention program (1 hour/week) to treat insistence on sameness (e.g., difficulty tolerating changes in routine) in youth with autism spectrum disorder (ASD). Treatment will be delivered via secure telemedicine platform and consist of a combination of parent-training and parent-mediated intervention with the child.

What is being tested

• Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth (behavioral)

Sponsor: Stanford University · Participants: 44 · Started: Jul 11, 2024

Contact the study team

• Emily Ferguson, PhD · Phone: 650-736-1235
• Robin Libove, BS · Phone: 650-736-1235

Official record on ClinicalTrials.gov — NCT06362733

Locations in the U.S.

Conditions

• Autism Spectrum Disorder
• Autism

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.