Home › Retinal Disorders › NCT06380075

COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Participants 18 years and older with a clinical and/ or genetic diagnosis of IRD recruited either from the clinic and/or the Inherited Ocular Disease Registry to participate in this trial
* Participants that are willing to participate as evidenced by signing the written informed consent

Exclusion Criteria:

* Presence of ocular conditions other than an IRD which may affect the quality of ocular imaging including but not limited to advanced cataracts, corneal disorders, nystagmus, vitreous hemorrhage, or poor dilation
* Presence of ocular conditions other than an IRD which may affect interpretation of retinal imagining including but not limited to epiretinal membrane, choroidal neovascular membrane, or macular scarring
* Patients with advanced IRDs who are unable to fixate for imaging
* Patients unable to tolerate ocular imaging
* Patients who do not wish to participate

About the study

The goal of this research study is to compare two ultrawide field cameras to the gold standard imaging system to evaluate the back of the eye. The main question it aims to answer is the same results and information can be acquired from all of the cameras for evaluating and monitoring inherited retinal diseases (IRDs).

Participants will:

* undergo pupillary dilation * have photographs taken of the inside of the eyes using three different cameras

What is being tested

• Spectralis FAF imaging (device)
• Optos imaging (device)
• Clarus imaging (device)

Sponsor: University of Wisconsin, Madison · Participants: 50 · Started: Aug 29, 2024

Contact the study team

• Angie Adler · Phone: 608-265-7557

Official record on ClinicalTrials.gov — NCT06380075

Locations in the U.S.

Conditions

• Retinal Disorders

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.