Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke
Who can join
Ages 18 to 80 · All sexes
Full eligibility criteria
Inclusion Criteria: * History of chronic stroke (more than 6 months post-stroke) with weakness on one side * Ability to ambulate over ground for 10 meters with or without a single cane, and/or ankle-foot orthosis * Ability to tolerate 10 minutes of standing Exclusion Criteria: * Presence of cognitive impairment (score of 22/30 on the Montreal Cognitive Assessment scale (MoCA)) * Presence of aphasia (score of 71/100 on the Mississippi Aphasia Screening Test (MAST)) * Excessive spasticity in lower limbs (score of \> 3 on the Modified Ashworth Scale * Severe cardiovascular and pulmonary disease affecting gait and balance * History of recurrent fractures or known orthopedic problems in the lower extremities (i.e. heterotopic ossification) affecting gait and balance * Concomitant central or peripheral neurological injury (i.e. traumatic head injury or peripheral nerve damage in lower limbs) affecting gait and balance * Evidence of cerebellar ataxia * Presence of unhealed decubiti or other skin compromise * Enrollment in concurrent physical therapy or research involving gait or balance training * Use of braces/orthotics crossing the knee joint * Known pregnancy
About the study
Stroke is a leading cause of disability in the United States, affecting approximately 795,000 people annually. The Veteran's Health Administration provides over 60,000 outpatient visits for stroke-related care annually at a cost of over $250 million. Among ambulatory people with chronic stroke (PwCS), impaired balance is a common health concern that substantially limits mobility (those with the worst balance walk the least). This project will explore adaptive strategies employed by PwCS in balance challenging environments and if a novel gait training intervention using a robotic device to amplify a person's self-generated movements can improve walking balance. The development of effective interventions to increase walking balance among PwCS will positively impact Veterans' health, quality of life, and ability to participate in walking activities.
What is being tested
- High intensity gait training in varying external environments (behavioral)
- Treadmill walking in varying external environments (behavioral)
Sponsor: VA Office of Research and Development · Participants: 30 · Started: Aug 15, 2024
Contact the study team
- Keith E Gordon, PhD · Phone: (708) 202-8387
Official record on ClinicalTrials.gov — NCT06400186
Locations in the U.S.
| Illinois | Northwestern University, Chicago (Not yet recruiting) Edward Hines Jr. VA Hospital, Hines, IL, Hines |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.