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Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia

RecruitingHealthy volunteers welcome

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* At least 18 years of age
* Persons with acquired aphasia are defined as those with a language impairment following left hemisphere brain injury (most likely a stroke).
* Neurotypical adults need to be either young (ages 18-30 years) or older (\> 60 years)
* Native (or primary) speakers of English

Exclusion Criteria:

* Prior neurological or psychiatric diagnoses or developmental disabilities before the onset of aphasia
* do not speak English fluently

About the study

The proposed research is relevant to public health because stroke is a leading cause of long-term disability among older adults and communication impairments resulting from stroke have a significant negative impact on quality of life. By seeking to better understand post-stroke aphasia, this project lays the groundwork for development of new interventions, and aligns with NIDCD's priority areas 1 (understanding normal function), 2 (understanding diseases), and 3 (improving diagnosis, treatment, and prevention).

What is being tested

Sponsor: University of Maryland, College Park · Participants: 350 · Started: Aug 1, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06405594

Locations in the U.S.

MarylandUniversity of Maryland, College Park

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.