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Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer
OUR Stomach Health Project: A Pilot Study to Evaluate the Feasibility of Stomach Cancer Risk Assessment for Early Detection and Secondary Prevention
Who can join
Ages 40 to 80 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Documented informed consent of the participant and/or legally authorized representative * Assent, when appropriate, will be obtained per institutional guidelines * Age: ≥ 40 years to ≤ 80 years * Identify as a racial minority either Asian, Hispanic, or Black American * Willingness to: * Provide blood samples and undergo upper endoscopy Exclusion Criteria: * Identify as Non-Hispanic White * History of gastric cancer * Known premalignant lesions of the stomach * History of upper endoscopy within 2 years * Women of childbearing potential: Pregnant/ nursing * An employee who is under the direct/indirect supervision of the principal investigator (PI)/a coinvestigator/the study manager * A direct study team member
About the study
This clinical trial evaluates the usefulness of various risk assessment tests, including Helicobacter pylori (H. pylori) breath testing, questionnaires, and endoscopies for identifying participants at high risk for stomach cancer. H. pylori is a bacteria that causes stomach inflammation and ulcers in the stomach. People with H. pylori infections may be more likely to develop cancer in the stomach. H. pylori breath testing can help identify the presence of H. pylori infection in a participant and help identify if the participant may be at a higher risk of developing stomach cancer. An endoscopy uses a thin, flexible lighted tube that is inserted inside the esophagus, stomach, and first part of the small intestine. This allows the doctor to see and look for abnormal areas that may need to be biopsied. Risk assessment including H. pylori evaluation, questionnaires, and endoscopies may help identify participants at high risk for stomach cancer and may be a useful screening tool for earlier stomach cancer diagnosis.
What is being tested
- Biopsy (procedure)
- Biospecimen Collection (procedure)
- Breath Test (procedure)
- Esophagogastroduodenoscopy (procedure)
- Questionnaire Administration (other)
Sponsor: City of Hope Medical Center · Participants: 240 · Started: Jun 27, 2024
Contact the study team
Official record on ClinicalTrials.gov — NCT06408220
Locations in the U.S.
| California | City of Hope Medical Center, Duarte |
Conditions
From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.