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EOIFP Block Versus OSTAP Block for Upper Abdominal Surgery

A Feasibility Pilot Study Assessing the Effects of External Oblique Intercostal Fascial Plane Block Versus Subcostal TAP Block for Upper Abdominal Surgery: A Randomized, Controlled Trial

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Written informed consent;
* 18-85 years old;
* ASA Physical Status 1-3
* Scheduled for elective open upper abdominal surgery with supraumbilical incision (gastrectomy, hepatectomy, pancreatectomy, splenectomy, supraumbilical ventral hernia repair).
* Anticipated hospitalization of three nights;
* Expected requirement for parenteral opioids for at least 48 hours for postoperative pain

Exclusion Criteria:

* Hepatic disease, e.g. twice the normal levels of liver enzymes;
* Chronic kidney disease according to GFR (may be stage 3 or worse as defined by a GFR \<60
* Allergic reaction to study medications;
* Women who are pregnant or breastfeeding;
* Nephrectomy or lower abdominal surgeries such as hysterectomy, colorectal surgeries
* Patient refusal

About the study

The investigators propose a single-center, assessor blinded, randomized control trial to compare the efficacy of external oblique fascial plane (EOIFP) block versus Oblique Subcostal Transversus Abdominis Plane (OSTAP) block for patients undergoing open upper abdominal surgery at Cleveland Clinic Main Campus.

What is being tested

• Oblique Subcostal Transversus Abdominis Plane Block (procedure)
• External Oblique Intercostal Fascial Plane block (procedure)

Sponsor: The Cleveland Clinic · Participants: 100 · Started: Jun 26, 2024

Contact the study team

• Fabio Rodriguez, MD · Phone: 216-444-9950
• Ehab Farag, MD · Phone: 216 870-8719

Official record on ClinicalTrials.gov — NCT06409156

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.