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Feasibility and Acceptability of Mindful Self-Compassion Among Transgender and Nonbinary Young Adults

RecruitingHealthy volunteers welcome

Evaluating the Feasibility and Acceptability of Mindful Self-Compassion Among Transgender and Nonbinary Young Adults

Who can join

Ages 18 to 29 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* transgender, nonbinary, genderqueer (or another non-cisgender identity)
* have reliable access to a smart phone or computer/tablet and the Internet and is reasonably able to make the time commitment required of the program (self-report)
* speak and understand English

Exclusion Criteria:

* has had formal mindfulness training (i.e. mindfulness-based stress reduction course) or engages in regular mindfulness practice (15 minutes more than twice a week for the last six months or more)
* Score 15 or higher on the patient health questionnaire-8 (PHQ-8)
* Score 2 or higher on the Columbia Suicide Severity Rating Scale
* Experienced an acute physical health crisis (e.g., chemotherapy, recovery from severe injury) (Germer \& Neff, 2019, p. 80) in the past year
* Head trauma, seizure, or loss of consciousness in the past 6 months
* Reports a history of trauma AND Scores 14 or higher on Post-Traumatic Checklist, 6-item Civilian version
* Reports a diagnosis of a personality disorder
* Reports a diagnosis of schizophrenia or a history of psychosis
* Reports acute panic attack in the past month and history of acute panic attacks with concern/worry about having another one in the future OR Reports severe social anxiety which would make attending class too difficult
* Reports an acute episode of psychosis or suicide attempt in the past 12 months
* Has engaged in non-suicidal self-injury in the past 6 months
* Currently prescribed antipsychotic medications, benzodiazepine (equivalent to 30mg diazepam/day) or opioids (\>40mg morphine equivalent/day)
* Prescribed any other psychiatric medication, including medication for opioid use disorder, whose dose has been changed in the past 8 weeks or is anticipated to change in the next 2 months.
* Currently engage in harmful drinking (5 or more drinks on one occasion (Flentje et al., 2020) more than once in the past 2 weeks; OR have any concerns about the expectation to not be using substances during group sessions
* has undergone detoxification from alcohol or other drugs and has been in sustained remission (with or without medication) for less than 1 year
* Has been hospitalized overnight for mental health related reasons in the past year (any diagnoses except bipolar disorder) OR have a diagnosis of bipolar disorder and have had an episode of mania or have been hospitalized in the past 2 years
* Reports any other acute physical or mental illness symptoms that may make group participation difficult

About the study

The goal of this single-arm feasibility study is to evaluate the feasibility and acceptability of an 8-week mindful self-compassion intervention and associated data-collection plan among transgender and nonbinary young adults. Participants will be asked to:

* Complete weekly 2.5-hour virtual classes for 8 weeks and a 4-hour virtual retreat * Practice specific activities in between classes for 20-30 minutes a day * Answer survey questions before starting the intervention, half-way through the intervention, after the intervention, and 3-months after the intervention ends.

What is being tested

Sponsor: University of Rhode Island · Participants: 50 · Started: Jun 12, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06409975

Locations in the U.S.

Rhode IslandN/A-- All study activities being conducted virtually, Providence

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.