Home › Aneurysms › NCT06417177

Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia

Who can join

Ages 18 to 70 · Women · Healthy volunteers welcome

Inclusion Criteria:

* Female assigned at birth
* Pre, peri- or post-menopausal
* Healthy weight (BMI ≥18 and ≤30 kg/m2)

Exclusion Criteria:

* Male (assigned at birth)
* Pregnancy, breastfeeding
* Use of hormone replacement therapies
* Hysterectomy
* Body mass index \>30 kg/m2
* Diagnosed sleep apnea
* Current smoking/Nicotine/Drug use
* Nerve/neurologic disease
* Cardiovascular, hepatic, renal, respiratory disease
* Blood pressure ≥140/90 mmHg
* Diabetes, Polycystic ovarian syndrome
* Communication barriers
* Prescription medications
* Malignant cancer

About the study

The purpose of this study is to examine hypoxic vasodilation and the role of beta-adrenergic receptors in younger premenopausal, perimenopausal, and older postmenopausal women.

What is being tested

• Placebo (drug)
• Propranolol (drug)
• Gemtesa (drug)

Sponsor: University of Missouri-Columbia · Participants: 75 · Started: Jun 3, 2024

Contact the study team

• Jacqueline Limberg · Phone: 573-882-2544

Official record on ClinicalTrials.gov — NCT06417177

Locations in the U.S.

Conditions

• Aneurysms

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.