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Head-Cancelled Virtual Reality for Ocular Cranial Nerve Palsies

RecruitingHealthy volunteers welcome

Head-Cancelled Virtual Reality for Rehabilitation of Ocular Cranial Nerve Palsies

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Full eligibility criteria
OCNP Group Inclusion Criteria:

* Presence of OCNP in one eye with 50% range-of-motion limitation or worse
* Able to provide informed consent and will be able to fluently read and understand spoken English

OCNP Group Exclusion Criteria:

* Presence of bilateral OCNP
* Range of motion better than 50%
* Visual acuity worse than 20/100 in either eye
* Greater than 4-line difference in visual acuity between the eyes,
* Structural anomalies or sensory sensitivities (e.g. visual motion sensitivity) that would prevent them from wearing or tolerating a VR headset

Participants will be excluded if they are unable to participate if inclusion criteria are not met.

Normal Group Inclusion Criteria:

* Absence of OCNP or other neurological or neuro-ophthalmic diseases
* No strabismus
* Have normal or near-normal vision with glasses or contact lenses.
* Be able to provide informed consent and will be able to fluently read and understand spoken English

Normal Group Exclusion Criteria:

* Visual acuity worse than 20/100 in either eye
* Greater than 4-line difference in visual acuity between the eyes
* Structural anomalies or sensory sensitivities (e.g. visual motion sensitivity) that would prevent them from wearing or tolerating a VR headset
* Known inability to tolerate visual testing of at least 20 minutes continuously.

About the study

This study is investigating whether eye exercises for abducens palsy and internuclear ophthalmoplegia increase ocular range of motion in the paretic direction when performed in virtual reality under head-cancelled compared to head-active conditions.

What is being tested

Sponsor: Kevin Houston · Participants: 40 · Started: Sep 10, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06417216

Locations in the U.S.

FloridaBrooks Rehabilitation Hospital, Jacksonville
MassachusettsVision Source of Worcester, Worcester

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.