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PReSeRVE-HD: Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis

RecruitingObservational study

PReSeRVE-HD: PRospective, Multicenter, Observational Study of the Merit HeRO® Graft and Super HeRO® EValuated in End-Stage Renal Disease Patients on HemoDialysis

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Key Inclusion Criteria:

* Subject provides written informed consent
* Subject is ≥ 18 years
* Subject is end-stage renal disease patient on hemodialysis.
* Subject is treated with HeRO Graft or Super HeRO System in accordance with device instructions for use (IFU)

Key Exclusion Criteria:

* Subject has a previously placed HeRO or Super HeRO device that is undergoing revision or replacement
* Subject has a topical or subcutaneous infection associated with the implantation site
* Subject has known or suspected systemic infection, bacteremia or septicemia

About the study

The goal of this observational study is to increase the understanding of the safety and performance of Merit Medical's HeRO Graft System (HeRO) and Super HeRO Adaptor and Support Seal System (Super HeRO) devices. This study includes adults that are being treated with one of these devices as part of their regular medical care for maintaining long-term dialysis access when all other dialysis access options have failed. If participants in the study are not seen for a standard of care clinic visit during the 4 visit timepoints over 2 years, the participant will be followed by phone to check their current health and dialysis status.

What is being tested

Sponsor: Merit Medical Systems, Inc. · Participants: 100 · Started: Jul 28, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06422871

Locations in the U.S.

District of ColumbiaMedStar Washington Hospital Center, Washington D.C.
FloridaSarasota Memorial Health Care System, Sarasota
North CarolinaWakeMed, Raleigh
PennsylvaniaUniversity Pittsburgh Medical Center, Pittsburgh
TexasBaylor Scott & White Heart and Vascular Hospital - Dallas, Dallas
Houston Methodist Hospital, Houston
VirginiaSentara Norfolk General Hospital, Norfolk

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.