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Characterizing the Impact of Presbyphonia on Social Interaction

Who can join

Ages 65 and older · All sexes

Inclusion Criteria:

* Diagnosis of presbyphonia with findings of presbylaryngis on videostroboscopy, with findings of bilateral true vocal fold atrophy and normal vocal fold motion bilaterally
* Able to complete all questionnaires and voice assessment tasks
* Normal to mild hearing loss in aided condition (with hearing aids)

Exclusion Criteria:

* Liquid dysphagia or pneumonia in the last year
* Vocal fold lesion/scar/motion impairment
* Neurologic disorder affecting the voice
* Montreal cognitive assessment score \<26 or \<25 if 12 or fewer years of formal education

About the study

The purpose of this study is to determine if presbyphonia, or voice disorder caused by age-related change in the larynx, is associated with change in social interaction. This proposal investigates the impact of voice impairment in older adults on social interaction, loneliness, social disconnectedness, and depression. A series of questionnaires, voice assessments, and interviews will be performed to improve our understanding of how voice disorders affect older adults and how treatment of voice impairment with voice therapy may improve quality of life.

What is being tested

• PhoRTE Program (other)
• University of California Los Angeles (UCLA) Loneliness Scale (other)
• Social Disconnectedness Scale (other)
• Patient Health Questionnaire 9 (other)
• Aging Voice Index (other)
• The Edmonton Frail Scale (other)

Sponsor: Matthew R. Hoffman · Participants: 25 · Started: Jan 10, 2025

Contact the study team

• Matthew R Hoffman, MD, PhD · Phone: 319-356-2201
• Emma L Thayer, BS · Phone: 319-678-7518

Official record on ClinicalTrials.gov — NCT06441136

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.