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Effects of THC on Alcohol Consumption and Neural Correlates of Reward
Who can join
Ages 21 to 40 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Drink alcohol * Use cannabis * Contact site for additional details Exclusion Criteria: * MRI contraindications (implanted metal, weight \> 315 lb, etc.). * Contact site for additional details
About the study
Alcohol and cannabis are often used together such that their effects overlap, but little is known about the neural mechanisms that underlie simultaneous use. High doses of THC have not been well-studied in the laboratory, and it is unclear how high doses of THC may impact alcohol consumption patterns. The proposed study will explore the effects of oral THC (20mg dronabinol) vs. placebo on neural reward, alcohol self-administration and naturalistic co-use patterns.
What is being tested
- Dronabinol Pill (drug)
- Placebo (drug)
Sponsor: University of Colorado, Denver · Participants: 28 · Started: Jul 1, 2024
Contact the study team
- Elnaz Nourollahimoghadam · Phone: 3037246020
Official record on ClinicalTrials.gov — NCT06446479
Locations in the U.S.
| Colorado | University of Colorado Anschutz Medical Campus, Aurora |
From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.