Aesthetic Outcome of Intra-dermal Versus Transcutaneous Purse-string Closure
Aesthetic Outcome of Intra-dermal Versus Transcutaneous Purse-string Closure: a Randomized Evaluator-blinded Split-wound Comparative Effectiveness Trial
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * 18 years of age or older * Able to give informed consent themselves * Patient scheduled for cutaneous surgical procedure on the head, neck, trunk, or extremities with predicted purse-string closure. * Willing to return for follow up visit Exclusion Criteria: * Incarceration * Under 18 years of age * Pregnant Women
About the study
The purpose of this study is to determine whether intra-dermal versus transcutaneous purse-string closures have similar scar cosmesis and post-operative complications. The investigators will use a split wound model, where half of the wound will be closed with intra-dermal purse-string sutures and the other half will be closed with a transcutaneous purse-string sutures. Three-months post-surgery, the scar will be evaluated via the patient observer scar assessment scale (POSAS), a validated scar instrument, as well as the trace-to-tape method, an objective outcome measure for linear postoperative scars. Any adverse events will also be recorded.
What is being tested
- Intra-dermal purse-string closure (procedure)
- Transcutaneous purse-string closure (procedure)
Sponsor: University of California, Davis · Participants: 73 · Started: Oct 14, 2025
Contact the study team
- Salsala Nasim, BS · Phone: 916-551-2636
Official record on ClinicalTrials.gov — NCT06448481
Locations in the U.S.
| California | University of California, Davis - Dermatology Department, Sacramento |
Conditions
From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.