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Daily Eating Patterns for Total Health Study
Effect of Time-based Energy Intake Goals on Weight Loss During Obesity Treatment
Who can join
Ages 25 to 60 · All sexes
Full eligibility criteria
Inclusion Criteria: * Body mass index (BMI) between 27 and 45 kg/m2. Exclusion Criteria: * Report not regularly (\>/= 5 days/wk) consuming energy (\>/= 100 kcal) prior to 12 pm, and not being able to consume energy every day (\>/= 50 kcal) within one hour of awakening. * Report taking sleep medication or not regularly (\>/= 5 nights/wk) getting at least 6 hrs of total sleep. * Report being a shift workers/alternative shift workers that work outside of 7 am and 7 pm. * Report being diagnosed with type 1, or type 2 diabetes and taking medication that requires eating to occur at certain time periods. * Report a heart condition, chest pain during periods of activity or rest, or loss of consciousness on the Physical Activity Readiness Questionnaire (PAR-Q). Individuals reporting joint problems, prescription medication usage, or other medical conditions that could limit exercise will be required to obtain written physician consent to participate. * Report being unable to walk for 2 blocks (1/4 mile) without stopping. * Report major psychiatric diseases or organic brain syndromes. * Report currently participating in a weight loss program and/or taking weight loss or appetite regulation medication or lost \>/= 5% of body weight during the past 6 months. * Report having bariatric surgery for weight loss/planning to have bariatric surgery in the next 12 months. * Report being pregnant, lactating, \< 6 months post-partum or plan to become pregnant (next 12 months). * Report planning to move outside of the metropolitan area within the time frame of the investigation. * Do not have daily access to PC with internet or smartphones (needed for self-monitoring).
About the study
The goal of this randomized controlled trial is to learn how the time of day when calories are eaten affects weight loss in the long-term (12 months). The main aims are to learn:
1. The influence of time-based energy intake goals on longer-term weight loss. 2. The influence of time-based energy intake goals on eating temporal patterns, sleep regularity, and appetite regulation.
Researchers will compare whether goals to eat most of a person's calories in the morning or evening work to treat obesity.
Participants will:
1. Eat a reduced-calorie, low-fat diet (some participants will have goals to eat their calories at certain times of day based on their group) 2. Be physically active at least 200 minutes 3. Receive a cognitive behavioral intervention
What is being tested
- DEPTH (behavioral)
- DEPTH-Morning (behavioral)
- DEPTH-Evening (behavioral)
Sponsor: The University of Tennessee, Knoxville · Participants: 174 · Started: Jul 16, 2024
Contact the study team
- Hollie A Raynor, PhD · Phone: 865-974-9126
Official record on ClinicalTrials.gov — NCT06455995
Locations in the U.S.
| Tennessee | Healthy Eating and Activity Laboratory, Knoxville |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.