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Daily Eating Patterns for Total Health Study

Recruiting

Effect of Time-based Energy Intake Goals on Weight Loss During Obesity Treatment

Who can join

Ages 25 to 60 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Body mass index (BMI) between 27 and 45 kg/m2.

Exclusion Criteria:

* Report not regularly (\>/= 5 days/wk) consuming energy (\>/= 100 kcal) prior to 12 pm, and not being able to consume energy every day (\>/= 50 kcal) within one hour of awakening.
* Report taking sleep medication or not regularly (\>/= 5 nights/wk) getting at least 6 hrs of total sleep.
* Report being a shift workers/alternative shift workers that work outside of 7 am and 7 pm.
* Report being diagnosed with type 1, or type 2 diabetes and taking medication that requires eating to occur at certain time periods.
* Report a heart condition, chest pain during periods of activity or rest, or loss of consciousness on the Physical Activity Readiness Questionnaire (PAR-Q). Individuals reporting joint problems, prescription medication usage, or other medical conditions that could limit exercise will be required to obtain written physician consent to participate.
* Report being unable to walk for 2 blocks (1/4 mile) without stopping.
* Report major psychiatric diseases or organic brain syndromes.
* Report currently participating in a weight loss program and/or taking weight loss or appetite regulation medication or lost \>/= 5% of body weight during the past 6 months.
* Report having bariatric surgery for weight loss/planning to have bariatric surgery in the next 12 months.
* Report being pregnant, lactating, \< 6 months post-partum or plan to become pregnant (next 12 months).
* Report planning to move outside of the metropolitan area within the time frame of the investigation.
* Do not have daily access to PC with internet or smartphones (needed for self-monitoring).

About the study

The goal of this randomized controlled trial is to learn how the time of day when calories are eaten affects weight loss in the long-term (12 months). The main aims are to learn:

1. The influence of time-based energy intake goals on longer-term weight loss. 2. The influence of time-based energy intake goals on eating temporal patterns, sleep regularity, and appetite regulation.

Researchers will compare whether goals to eat most of a person's calories in the morning or evening work to treat obesity.

Participants will:

1. Eat a reduced-calorie, low-fat diet (some participants will have goals to eat their calories at certain times of day based on their group) 2. Be physically active at least 200 minutes 3. Receive a cognitive behavioral intervention

What is being tested

Sponsor: The University of Tennessee, Knoxville · Participants: 174 · Started: Jul 16, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06455995

Locations in the U.S.

TennesseeHealthy Eating and Activity Laboratory, Knoxville

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.