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Optimizing Infection Prophylaxis Prior to Shoulder Surgery

Who can join

Ages 18 to 89 · Men · Healthy volunteers welcome

Inclusion Criteria:

* English speaking

Exclusion Criteria:

* Self report very sensitive skin
* Allergic to chlorhexidine
* Used antibiotics in the last three months
* Used acne treatment in the last three months
* Wounds on your shoulders

About the study

The goal of this interventional study is to determine the amount of skin C. acnes reduction with increased pressure during the chlorhexidine gluconate, brand name ChloraPrep, application. The main question it aims to answer is:

Does changing the pressure applied during the ChloraPrep application impact the amount of C. acnes bacteria on the skin after one hour? Researchers will compare ChloraPrep applied at a pressure similar to a gentle wipe to ChloraPrep applied at a pressure similar to a massage to see if wash the amount of C. acnes on the skin after one hour is different.

Participants will have one shoulder washed with ChloraPrep using pressure meant to impact the dermal layer, similar to a gentle wipe, and the other shoulder washed with ChloraPrep using pressure meant to impact the subdermal layer, similar to a massage. Participants will have swabs taken of their skin before the ChloraPrep application and again one hour after application to look for the amount of C. acnes on the skin.

What is being tested

• Chlorhexidine Gluconate (drug)

Sponsor: University of Washington · Participants: 40 · Started: Aug 31, 2024

Contact the study team

• Anastasia Whitson · Phone: 206-755-7847

Official record on ClinicalTrials.gov — NCT06464770

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.