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Speech Motor Learning and Retention (Master Protocol)

Sensorimotor Basis of Speech Motor Learning and Retention

Who can join

Ages 18 to 40 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Fluent English speakers
* Right-handed
* Normal hearing
* No speech disorder or reading disability

Exclusion Criteria:

* Cardiac pacemaker
* Aneurysm clip
* Heart or Vascular clip
* Prosthetic valve
* Metal implants
* Metal in brain, skull, or spinal cord
* Implanted neurostimulator
* Medication infusion device
* Cochlear implant or tinnitus (ringing in ears)
* Personal and/or family history of epilepsy or other neurological disorders or history of head concussion
* Psychoactive medications
* Pregnancy

About the study

The overall goal of this research is to test a new model of speech motor learning, whose central hypothesis is that learning and retention are associated with plasticity not only in motor areas of the brain but in auditory and somatosensory regions as well.

What is being tested

• continuous theta-burst stimulation (cTBS) (device)
• Adaptation (behavioral)
• Single pulse Transcranial magnetic stimulation (TMS) (device)
• fMRI (device)

Sponsor: Yale University · Participants: 330 · Started: Oct 1, 2024

Contact the study team

• Michael Stern · Phone: 2038656163

Official record on ClinicalTrials.gov — NCT06467292

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.