ECMO ABI Detection With Hyperfine

Recruiting

Low-Field Bedside MRI for Detection of Acute Brain Injury in Pediatric Extracorporeal Membrane Oxygenation

Who can join

0 Days – 17 Years · All sexes

Full eligibility criteria

Inclusion Criteria:

* Participants that will be or are admitted to the Pediatric Intensive Care Unit, Cardiac Intensive Care Unit, or the Neonatal Intensive Care Unit
* Ages 0-17 years
* Participants that are at high risk for undergoing ECMO or are currently undergoing venovenous or venoarterial ECMO

  • High risk participants include, but are not limited to:
* Undergoing cardiac surgery
* Congenital heart disease
* Congenital diaphragmatic hernia
* Refractory hypoxemic and/or hypercarbic respiratory failure
* Vasoactive-refractory shock

Exclusion Criteria:

* Pregnancy
* Any patient who has a contraindication to having an MRI
* Patients with a passive or active implant will:

  * First be reviewed on MRISafety.com to determine MR conditionality
  * If device is listed as Conditional or Unsafe for a 1.5T or a 3T, device will then be reviewed by MRI Safety Officer or MRI Physician Section chief to determine true conditionality for the portable MRI

About the study

The primary objective is to characterize the prevalence and type of ABI following cannulation for pediatric patients who require ECMO support. The secondary objective is to describe the time course and rates of ABI using ultralow-field bedside MRI relative to both duration of ECMO support and clinical imaging obtained in routine care of pediatric ECMO patients.

What is being tested

Hyperfine (device)

Sponsor: Children's Mercy Hospital Kansas City · Participants: 40 · Started: Jul 23, 2024

Contact the study team

Maura Sien, MSML, CCRC · Phone: 8163028311

Official record on ClinicalTrials.gov — NCT06469801

Locations in the U.S.

Missouri

Children's Mercy, Kansas City

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.