Home › Hyperthermia › NCT06475339
Predicting Responses to Exhausting, Prolonged, And Repeated Exercise Demands (PREPARED) for Heat
Who can join
Ages 18 to 39 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Healthy individuals * Physically active Exclusion Criteria: * History of cardiovascular, metabolic (such as clinical thyroid disease), respiratory, neural, or renal disease * Hypertensive (systolic blood pressure \> 139 mmHg, diastolic blood pressure \> 89 mmHg) or tachycardic (heart rate \> 100 bpm) during the screening visit * Taking medications or supplements known to effect physiologic responses to exercise or thermoregulation (e.g., beta blockers, omega-3 fatty acids, statins, aspirin) * Tobacco or nicotine use currently or in the past six months * Musculoskeletal injury expected to impact exercise in the protocol * A positive pregnancy test at any point in the study * Study physician discretion based on any other medical condition or medication * Inability to understand or follow instructions or the protocol * Gastrointestinal disease or previous surgery prohibiting core temperature capsule use. Participants with a contraindication can opt to insert the pill rectally as a suppository.
About the study
The overall goal of this project is to identify a work/rest cycle that allows for faster mission completion needed in emergency situations, compared to current Army heat guidance, while mitigating heat strain and neuromuscular fatigue. This project will determine the trade-off between faster mission completion and risk of heat strain and physical performance decrements. Completion of this project will allow military leaders to make informed decisions by understanding the impact of their choices on the magnitude of physical performance decrements and expected heat casualties, setting up hot weather missions for success.
What is being tested
- 30/30 work/rest cycle (other)
- 30/20 work/rest cycle (other)
- 40/30 work/rest cycle (other)
- 20/12 work/rest cycle (other)
Sponsor: State University of New York at Buffalo · Participants: 24 · Started: Nov 1, 2024
Contact the study team
- Riana R Pryor, PhD · Phone: 7168295456
Official record on ClinicalTrials.gov — NCT06475339
Locations in the U.S.
| New York | Center for Research and Education in Special Environments, Buffalo |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.