Home › Ototoxicity › NCT06500975
Long Term Outcomes After Vestibular Implantation
Who can join
Ages 22 to 90 · All sexes
Full eligibility criteria
Inclusion Criteria * Adults older than 22 years old who * have previously been enrolled in Johns Hopkins University Institutional Review Board protocol NA\_00051349, IRB00335294 or IRB00346924 and * have previously been implanted with a vestibular implant under FDA IDE G150198
About the study
Although cochlear implants can restore hearing to individuals who have lost cochlear hair cell function, there is no widely available, adequately effective treatment for individuals suffering chronic imbalance, postural instability and unsteady vision due to bilateral vestibular hypofunction. Prior research focused on ototoxic cases has demonstrated that electrical stimulation of the vestibular nerve via a chronically implanted multichannel vestibular implant can partially restore vestibular reflexes that normally maintain steady posture and vision; improve performance on objective measures of postural stability and gait; and improve patient-reported disability and health-related quality of life. This single-arm open-label study extends that research to evaluate outcomes for up to 8 individuals with non-ototoxic bilateral vestibular hypofunction, yielding a total of fifteen adults (age 22-90 years at time of enrollment) divided as equally as possible between ototoxic and non-ototoxic cases.
What is being tested
- Labyrinth Devices MVIâ„¢ Multichannel Vestibular Implant System (device)
Sponsor: Johns Hopkins University · Participants: 32 · Started: Dec 1, 2024
Contact the study team
- Kelly Lane · Phone: 410-502-8047
- Charles C Della Santina, MDPhD · Phone: 410-502-8047
Official record on ClinicalTrials.gov — NCT06500975
Locations in the U.S.
| Maryland | Johns Hopkins School of Medicine, Baltimore |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.