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Can PLIA Reduce Early Post-operative Pain After PAO Surgery?

RecruitingPhase 2/3Healthy volunteers welcome

Peri-incisional Local Infiltration to Improve Pain Control After Periacetabular Osteotomy

Who can join

Ages 13 to 50 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Adolescent or young adult diagnosed with hip dysplasia indicated for PAO at University of Iowa Hospital and Clinics.

Exclusion Criteria:

* Unable to provide informed consent.
* Pregnant or breast-feeding individuals
* Prisoner or ward of the state
* Allergy or medical contradiction to any of the study medications
* Patients undergoing femoral osteotomy or surgical hip dislocation with PAO will be excluded

About the study

The goal of this clinical trial is to compare different peri-incisional local infiltrative anesthesia (PLIA) methods in patients ages 13 to 50 undergoing a periacetabular osteotomy (PAO). The main questions to answer here are:

1. Does PLIA impact post-operative pain after PAO? 2. Does PLIA impact pain medication usage as measured by morphine equivalent dosing (MED) after PAO? 3. Does the timing of PLIA administration impact post-operative pain and MED after PAO? Participants will be asked to complete some surveys; demographics survey, General Self-Efficacy Scale (GSE) and the Pain Resilience Scale. All other information will be gathered from the patients medical chart.

Researchers will compare three groups. 1.) Patients who do not receive PLIA. 2.) Patients who receive PLIA after their incision is closed. 3.) Patients who receive PLIA throughout PAO.

What is being tested

Sponsor: Michael C Willey · Participants: 120 · Started: Oct 3, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06519955

Locations in the U.S.

IowaUniversity of Iowa Health Care, Iowa City

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.