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The Aim of This Study is to Determine if Oocyte Sorting for Group Culture Using an Artificial Intelligence Image Analysis Tool (MagentaTM) Increases the Usable Blastocyst Yield and Subsequent Pregnancy in Patients Undergoing IVF
RecruitingObservational studyHealthy volunteers welcome
NiOS (Non-Invasive Oocyte Sorting) Study
Who can join
All ages · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Fresh MII oocytes * ICSI cycles with patient's or donor's sperm * Patient's or donor's oocytes * Full IVF cycle information available (including total number of oocytes retrieved, total MII oocytes, fertilization, embryo and blastocyst development, as well as ploidy status or implantation results, and 6-7 week ultrasound, if applicable) * Good quality images of MII oocytes taken with a specified camera (Basler) and Future Fertility Software * Single embryo transfers (SETs) at blastocyst stage. * Blastocyst freeze-all cycles Exclusion Criteria: * Severe male factor infertility (\<1 million motile), including surgically retrieved sperm. * ICSI cycles inseminating in vitro matured (IVM) oocytes * Rescue ICSI oocytes (oocytes failed standard IVF and are re-inseminated by ICSI) * Low quality images - Poor quality images on day of upload or before unblinding * Lack of correlating reproductive outcomes (full IVF lab results not available). * Autologous or donor frozen/warmed oocytes * Day 3 embryo transfers or cleavage stage embryo freezing * Patients with less than 6 mature oocytes
About the study
The aim of this study is to determine if oocyte sorting for group culture using an artificial intelligence image analysis tool (MagentaTM) increases the usable blastocyst yield and subsequent pregnancy in patients undergoing IVF.
What is being tested
- Magenta AI image analysis tool (other)
Sponsor: Ovation Fertility · Participants: 450 · Started: Jan 1, 2024
Contact the study team
Official record on ClinicalTrials.gov — NCT06521372
Locations in the U.S.
| Nevada | Ovation Fertility Las Vegas, Las Vegas |
| Ohio | Ovation Fertility Cincinnati, Cincinnati |
| Tennessee | Ovation Fertility - Nashville, Nashville |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.