🔎 Trials Near Me

Home › Stroke › NCT06523335

Increasing the Repertoire of Intermuscular Co-ordination Post Stroke Through EMG-Guided Human-Machine Interaction

RecruitingHealthy volunteers welcome

Intermuscular Coordination as a Novel Clinical Target for Stroke Neurorehabilitation

Who can join

Ages 40 to 75 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion criteria for aged matched healthy group

* Male or female whose age range between 40 and 75
* no known neurological injuries

Exclusion criteria for aged matched healthy group

* have an orthopedic disorder involving upper limbs;
* have a history of any neurologic disease;
* have any history of epilepsy of the potential participants and/or their family members;
* are unable to consent;
* are pregnant.

Inclusion criteria for stroke group

* male or female hemiparetic chronic stroke survivors;
* age ranging between 40-75 year;
* with single unilateral ischemic or hemorrhagic middle cerebral artery stroke;
* neurologically stable for \>6 months;
* have an expectation that current medication will be maintained without changes for at least 3 months. Stable use of anti-spasticity medication (e.g., baclofen, diazepam, tizanidine) is accepted;
* without severe spasticity (Modified Ashworth (MA) \<4);
* have not received botulinum toxin on the impaired arm within 3 months.

Exclusion criteria for stroke group

* have an orthopedic disorder involving upper limbs;
* cognitive impairment sufficient to interfere with informed consent or successful completion of the protocol (Montreal Cognitive Assessment (MoCA) score \< 26);
* a history of another neurologic disease;
* anesthesia of joint position sense in upper limbs;
* are pregnant or have a chance that they might be (self-reported);

About the study

The purposes of this study include:

1. \- To identify whether features of aberrant intermuscular coordination patterns can be used to predict motor impairment after stroke. 2. \- To test whether muscle synergies are malleable to a non-invasive EMG-guided exercise that induces changes in intermuscular coordination of upper extremity muscles after stroke.

What is being tested

Sponsor: University of Houston · Participants: 74 · Started: Oct 1, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06523335

Locations in the U.S.

TexasUniversity of Houston, Houston

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.