Home › Fecal Incontinence › NCT06532123
Mechanisms of Improving Fecal Continence Muscles Motor Function
RecruitingHealthy volunteers welcome
Mechanisms of Improving Fecal Continence Muscles Motor Function in Health and Disease
Who can join
Ages 18 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Healthy volunteers without past or present history of fecal incontinence * Patients age 18 years and older with reduced anal resting and or squeeze pressure, reflecting weakness of the anal sphincters who can perform the study Exclusion Criteria: * Any one less than 18 years old * Neurological disorders like dementia, cerebrovascular diseases * Muscle diseases like muscular dystrophy, myopathies * Inflammatory bowel disease or celiac disease * Neuro-muscular junction disorders/myasthenia gravis, Eaton-Lambert syndrome * Organ prolapse, large rectocele(\>2cm), rectal intussusception * Hip dysplasia or recent hip surgery and immobile patients. * Patients with complete normal anal resting and squeeze pressure * Impaired rectal evacuation (dyssynergy defecation) * Fecal incontinence completely due to loss of rectal sensation * Subjects unable to contract their external anal sphincter at all
About the study
The investigators hypothesize that different continence muscles have different fatigue characteristics and fatigue induced by resisted contractions will result in significant increase in contractility of the continence muscles and improvement of fecal incontinence severity.
What is being tested
- continence muscles resistance device (device)
Sponsor: Medical College of Wisconsin · Participants: 340 · Started: Jul 15, 2025
Contact the study team
Official record on ClinicalTrials.gov — NCT06532123
Locations in the U.S.
| Wisconsin | Medical College of Wisconsin, Milwaukee |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.