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Psychoeducational Intervention for Patients With Hepatocellular Carcinoma

HARMONY: A Psychoeducational Intervention to Reduce Psychological Distress and Improve Quality of Life for Patients With Hepatocellular Carcinoma

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Age ≥18 years
* New diagnosis of HCC within the last six months
* Ability to complete study procedures English

Exclusion Criteria:

* Incidentally diagnosed with HCC after liver transplantation
* Significant uncontrolled hepatic encephalopathy, cognitive impairment, or psychiatric disorder which will interfere with study participation
* Patients near the end of life for whom hospice is recommended

About the study

This study aims to refine and pilot test HARMONY, a psychoeducational intervention for patients with newly diagnosed hepatocellular carcinoma (HCC).

What is being tested

• HARMONY (behavioral)
• Enhanced usual care (other)

Sponsor: Massachusetts General Hospital · Participants: 50 · Started: Oct 28, 2024

Contact the study team

• Kelsey Lau-Min · Phone: 617-724-4000

Official record on ClinicalTrials.gov — NCT06541990

Locations in the U.S.

Conditions

• Liver Cancer (Hepatocellular Carcinoma)

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.