Home › NCT06553131
Median Versus Ulnar Nerve Quantitative Electromyography Neuromuscular Blockade Monitoring Comparison
Who can join
Ages 18 to 75 · All sexes
Full eligibility criteria
Inclusion Criteria: * Adults 18 - 75 years of age who are able to provide consent * Scheduled for elective surgery requiring muscle relaxation, in a supine position under general anesthesia, with an anticipated duration of at least 1.5 hours Exclusion Criteria: * Contraindication to rocuronium use * Comorbidities that may prolong the duration of neuromuscular blockade or alter pharmacodynamics and/or pharmacokinetics, such as: * Neuromuscular disease * Expected or known difficult airway * Rocuronium allergy * BMI \< 18.5 or \> 40 * History of adhesive allergy * Upper extremity weakness, limb deformity, or absence of all or part of an upper limb * Patients undergoing surgical procedures requiring cardiopulmonary bypass
About the study
Medications used to relax the muscles are used during surgery. The amount of muscle relaxation can monitored with devices that stimulate a specific nerve and evaluate the muscle response. The response to, and recovery from, medications that relax the muscles are best described for a nerve in the arm called the ulnar nerve. The investigators believe that other nerves in the arm, such as the median nerve, could be used to monitor the amount of muscle relaxation. The purpose of this study is to compare the muscle response at two different nerve sites after giving medications to relax the muscles.
This study is going to measure the depth of muscle relaxation during surgery at two different sites. The muscle response to stimulation of the ulnar nerve (located in the arm) will be compared to the muscle response to stimulation of the median nerve (also located in the arm).
What is being tested
- Neuromuscular Transmission Monitoring (device)
Sponsor: Loma Linda University · Participants: 32 · Started: Dec 26, 2024
Contact the study team
- Melissa D McCabe, MD, MSCR · Phone: 909 558 4475
- Michael Benggon, MD · Phone: 909 558 4475
Official record on ClinicalTrials.gov — NCT06553131
Locations in the U.S.
| California | Loma Linda University Troesch Medical Center, Loma Linda |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.