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A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB)

Who can join

6 Months · All sexes

Inclusion Criteria:

1. The subject or their respective legal guardian must have read, understood, and signed an Institutional Review Board (IRB) approved Informed Consent/Assent Form and must be able to and willing to follow study procedures and instructions.
2. Age 6 months or older at time of Informed Consent/Assent.
3. Prior genetic diagnosis of DEB due to mutation(s) in the collagen type VII alpha 1 chain (COL7A1) gene.

About the study

This study is a non-interventional, observational study that will evaluate the natural history of corneal abrasions in patients with Dystrophic Epidermolysis Bullosa (DEB).

Sponsor: Krystal Biotech, Inc. · Participants: 40 · Started: Aug 2, 2024

Contact the study team

• David Chien, MD · Phone: 412-586-5830
• Brittani Agostini, RN, CCRC · Phone: 412-586-5830

Official record on ClinicalTrials.gov — NCT06563414

Locations in the U.S.

Conditions

• Epidermolysis Bullosa Dystrophica
• Corneal Disorders

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.