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Analgesic Response to Opioids in Patients With Fibromyalgia After Conventional Acupuncture Versus Sham Acupuncture

Recruiting

Who can join

Ages 18 to 80 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Are 18 - 80 years old
* have been diagnosed with Fibromyalgia for more than 6 months
* Are already using chronic, continuous opioid therapy, including but not limited to the use of Hydrocodone (Norco), Oxycodone (Percocet), morphine, methadone or Tylenol #3 daily
* Have moderate to excruciating pain at baseline, determined by a 5 or greater score on the Visual Analogue Scale (VAS)

Exclusion Criteria:

* Are younger than 18 or older than 80 years old
* Have been diagnosed with a Substance Use Disorder (SUD)
* Pregnant
* Have an active litigation or worker's compensation case
* Have an active mental health diagnosis, such as bipolar disorder, psychosis, or suicidal ideation
* Are prescribed and actively using low dose Naltrexone . Have tried acupuncture in the last 6 months

About the study

This study aims to see whether acupuncture can help fibromyalgia patients by giving them acupuncture treatment and seeing whether acupuncture helps enhance the effects of an opioid.

What is being tested

Sponsor: University of California, Irvine · Participants: 45 · Started: Mar 15, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06571110

Locations in the U.S.

CaliforniaUCI Health Susan Samueli Integrative Health Institute, Irvine

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.