Home › Heat Illness › NCT06582680
Aging, Beta Blockers, and Thermoregulatory Responses
RecruitingPhase 4Healthy volunteers welcome
Who can join
Ages 65 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Healthy and free of any significant medical problems * Normal resting electrocardiogram * 65+ years of age * Controlled cholesterol of less than 200 mg/dl * Controlled blood pressure of less than 140/90 mmHg Exclusion Criteria: * Known diseases or other chronic conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, uncontrolled hypertension, and uncontrolled hypercholesterolemia * Serious abnormalities detected on routine screening * Taking prescribed medications or over-the-counter medications that have known influences on either cardiac function or sweating * Current smokers, as well as individuals who regularly smoked within the past 3 years * body mass index ≥31 kg/m2
About the study
This study will test the hypothesis that the drugs propranolol and metoprolol will result in greater increases in core body temperature during 3 hours of extreme heat exposure in older adults.
What is being tested
- Ambient Heat (other)
Sponsor: University of Texas Southwestern Medical Center · Participants: 22 · Started: Oct 4, 2024
Contact the study team
- Erin Harper, MS · Phone: 214-345-4737
- Courtney Kirby, RN · Phone: 214-345-6502
Official record on ClinicalTrials.gov — NCT06582680
Locations in the U.S.
| Texas | IEEM Texas Health Presbyterian Hospital Dallas, Dallas |
Conditions
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.