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Perceptual Influences From Smoking Cannabis: an Experimental Study

Exploring the Antecedents and Consequences of Cannabis Use in the Context of Coping: An Experimental Study

Who can join

Ages 21 to 65 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* 21-65 years of age
* Endorsement of at least some use of cannabis for coping purposes (\>1 on CMMQ)
* Regularly use flower cannabis products (i.e., ≥1x/week in the last 6 months)
* Proficient in English language
* At least occasional use of CBD+THC or CBD-dominant products (e.g., ≥1x/month)

Exclusion Criteria:

* Diagnosis or use of medications for substance use or psychotic disorders
* Report of other drug use (cocaine, opiates, methamphetamine) in the past 90 days or fail urine screen for any of these drugs
* Females cannot be pregnant or trying to become pregnant or nursing mothers
* Not able to provide informed consent

About the study

The purpose of the study is to better understand the effects of cannabis in relation to mental and physical states including its relationship with mood, cognition, perception including the experience of temperature and pain, and heart rate.

We expect that participants will be in this research study for approximately one week. The total amount of time that participants will spend completing study tasks will be about 2.5 hours across two separate in-person visits.

What is being tested

• Water Temperature Variation - WW (other)
• Water Temperature Variation - CW (other)

Sponsor: University of Colorado, Boulder · Participants: 166 · Started: Feb 17, 2025

Contact the study team

• Carillon Skrzynski, PhD · Phone: (734)788-2961

Official record on ClinicalTrials.gov — NCT06588582

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.