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Eating Disorders Genetics Initiative 2

RecruitingObservational studyHealthy volunteers welcome

Who can join

Ages 12 to 99 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* A lifetime history of anorexia nervosa, bulimia nervosa, binge-eating disorder, avoidant restrictive food intake disorders or no history of any disordered eating behavior, based on DSM-5 criteria algorithms
* Age 12-99 years, depending on country. (US enrollment age is 18-99)

Exclusion Criteria:

* History of subthreshold disordered eating behaviors.

About the study

The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes. The investigators are enrolling 20,000 new participants with anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), avoidant/restrictive food intake disorder (ARFID), and controls in the US, Mexico, Australia, New Zealand, Sweden, and Denmark. A primary study goal is to enroll at least 30% of participants from underrepresented groups. Participants are asked to complete a series of questionnaires and submit a saliva sample for genotyping. The goal is to better understand eating disorders and how they relate to each other so that better treatments can be developed.

What is being tested

Sponsor: University of North Carolina, Chapel Hill · Participants: 20,000 · Started: Oct 28, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06594913

Locations in the U.S.

North CarolinaUniversity of North Carolina at Chapel Hill, Chapel Hill

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.